Nat Clin Pract Oncol. Shore 21 August If a prolactinoma becomes large enough, it can cause visual changes especially decreased peripheral visionheadachesdepression or other mood changes, dizzinessnauseavomitingand symptoms of pituitary failurelike hypothyroidism. The skin becomes softer,  more susceptible to tearing and irritation from scratching or shaving, and slightly lighter in color because of a slight decrease in melanin. The Leydig Cell in Health and Disease. Progestogens have some antiestrogenic effects in the breasts, for instance decreasing expression of the estrogen receptor and increasing expression of estrogen- metabolizing enzymes    and for this reason, have been used to treat breast pain and benign breast disorders.
The pelvis retains some masculine characteristics, but the end result of HRT is wider hips than a cisgender man and closer to those of a cisgender woman.
Transgender hormone therapy (male-to-female)
Retrieved 13 June Anastrozole Exemestane Fadrozole Formestane Letrozole. Retrieved 31 July In half of these, the abnormalities continue for more than three months. The majority of these incidents occur during the first two years of treatment.
Estrogen ester Estradiol ester Estradiol acetate Estradiol benzoate Estradiol cypionate Estradiol dipropionate Estradiol enantate Estradiol undecylate Estradiol valerate Polyestradiol phosphate Estramustine phosphate estradiol normustine phosphate. Unsourced material may be challenged and removed. Male Reproductive Health and Dysfunction. In clinical trialscisgender women have used stem cells from fat to regrow their breasts after mastectomies. Many of the medications used in feminizing hormone therapy, such as estradiolcyproterone acetateand bicalutamideare substrates of CYP3A4 and other cytochrome P enzymes.